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Effective use of artificial neurons for the treatment of chronic neuropathic pain.
Francis R. Sparadeo PhD and Stephen D'Amato MD
Complex Regional Pain Syndrome
Brachial plexus neuropathy
Low back pain
Failed back surgery syndrome
Lumbar & sciatic pain
Narrow canal syndrome
Polyneuropathy due to other toxic agents
Mononeuritis of unspecified site
Unspecified chronic neuropathic pain
On December 1st, 2016, The Purple Bucket Foundation Inc. received notification that their application to have the medical device Scrambler Therapy® Technology MC-5A, CE Certification 0476, had been approved for supply in Australia and registered with the Australian Register of Therapeutic Goods. This paved the way for patients to be treated with Scrambler Therapy® Technology MC-5A throughout Australia.
Also enabling practitioners/operator’s direct access to the standard official training course, which certifies the operator to the correct methodology usage of Scrambler Therapy® Technology MC-5A and the dedicated software designed exclusively for Scrambler Therapy.
Postherpetic trigeminal neuralgia
Herpes zoster myelitis
Other Herpes zoster
Neoplasm related pain
Reflex sympathetic dystrophy
Myofascial pain syndrome
Acute pain (symptomatic treatment)
The Purple Bucket Foundation Inc. only promotes the medical device called Scrambler Therapy® Technology MC-5A,
CE Certification 0476 and the dedicated software designed exclusively for Scrambler Therapy.
a multicentre retrospective analysis.
Acute post-thoracotomy pain (symptomatic treatment)
Chronic post-thoracotomy pain
Other acute postoperative pain (symptomatic treatment)
Post-surgical chronic neuropathic pain
Information about the Scrambler Device
Video explaining how Scrambler changes pain therapy.
Scrambler Therapy® Technology was originally developed in Italy for treatment of chronic, neuropathic and oncologic pain resistant to opiates, anti-seizure medications, intravenous anaesthetics and other forms of treatment. Scrambler Therapy® is a non-invasive, non-pharmaceutical approach to pain therapy.
A pain specialist or a qualified physician certified in Scrambler Therapy who can correctly identify placement sites for treatment. The Scrambler device resembles an electrocardiogram medical device in appearance. It has five electrodes the physician places on the non-painful tissue near the site of pain but never on the site of pain.
It uses an electro cutaneous method (electrodes/leads on the skin) to comfortably stimulate (like a vibration) surface receptors on normal tissue that correspond to a dermatome type. This signal from normal tissue communicates a “non-pain” signal to the brain via the central nervous system that is specific to each individual. This signal is a synthetic signal of “non-pain” that the brain now recognizes as “normal self” because it travels the same pathways on the central nervous system that previously carried the “pain” message. It is for this reason, the inventor Giuseppe Marineo Ph.D., D.Sc. from the University of Rome Tor Vergata, Rome, Italy thought the name “Scrambler Therapy” was the most appropriate one.